发明名称 USE OF SULPHATED GLYCOLIPIDS AS PROMOTERS OF NEURITIC GROWTH AND MYELINATION AND INHIBITORS OF THE PROLIFERATION OF ASTROGLIA AND MICROGLIA
摘要 The invention relates to the use of a compound having formula I, in which R1 is an alkenyl group C5-C25 containing one ore more double carbon-carbon bonds, R2 is selected independently from the group consisting of methyl and fluorinated methyl, and R3 and/or R4 is a SO3M group, in which M is selected from the group consisting of hydrogen, alkali metal, ammonium and quaternary amine, the other being hydrogen or acyl, for the production of a drug for the treatment of central nervous system disorders selected from the group consisting of lesions caused by CNS trauma, demyelinating diseases, neuro-inflammatory diseases and mental disorders caused a low level of BDNF. The invention also relates to compounds having formula I, to methods for producing said compounds and to compositions containing same.
申请公布号 WO2014006250(A1) 申请公布日期 2014.01.09
申请号 WO2013ES70456 申请日期 2013.07.02
申请人 CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC);FUNDACION DEL HOSPITAL NACIONAL DE PARAPLEJICOS PARA LA INVESTIGACION Y LA INTEGRACION (FUHNPAIIN) 发明人 NIETO SANPEDRO, MANUEL;FERNANDEZ MAYORALAS, ALFONSO;DONCEL PEREZ, ERNESTO;GARCIA ALVAREZ, ISABEL
分类号 C07D309/14;A61K31/351;A61P25/00;C07D413/12;G01N21/64;G01N24/08 主分类号 C07D309/14
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