发明名称 |
USE OF SULPHATED GLYCOLIPIDS AS PROMOTERS OF NEURITIC GROWTH AND MYELINATION AND INHIBITORS OF THE PROLIFERATION OF ASTROGLIA AND MICROGLIA |
摘要 |
The invention relates to the use of a compound having formula I, in which R1 is an alkenyl group C5-C25 containing one ore more double carbon-carbon bonds, R2 is selected independently from the group consisting of methyl and fluorinated methyl, and R3 and/or R4 is a SO3M group, in which M is selected from the group consisting of hydrogen, alkali metal, ammonium and quaternary amine, the other being hydrogen or acyl, for the production of a drug for the treatment of central nervous system disorders selected from the group consisting of lesions caused by CNS trauma, demyelinating diseases, neuro-inflammatory diseases and mental disorders caused a low level of BDNF. The invention also relates to compounds having formula I, to methods for producing said compounds and to compositions containing same. |
申请公布号 |
WO2014006250(A1) |
申请公布日期 |
2014.01.09 |
申请号 |
WO2013ES70456 |
申请日期 |
2013.07.02 |
申请人 |
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC);FUNDACION DEL HOSPITAL NACIONAL DE PARAPLEJICOS PARA LA INVESTIGACION Y LA INTEGRACION (FUHNPAIIN) |
发明人 |
NIETO SANPEDRO, MANUEL;FERNANDEZ MAYORALAS, ALFONSO;DONCEL PEREZ, ERNESTO;GARCIA ALVAREZ, ISABEL |
分类号 |
C07D309/14;A61K31/351;A61P25/00;C07D413/12;G01N21/64;G01N24/08 |
主分类号 |
C07D309/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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