发明名称 |
KINASE SUBSTRATE SENSOR |
摘要 |
The disclosure relates to a cytoplasmic protein complex comprising: (a) a first recombinant fusion protein comprising a kinase, fused to a first interaction polypeptide; and (b) a second recombinant fusion protein comprising a domain comprising a reporter phosphorylation site, whereby the domain is fused to a second interaction polypeptide. The disclosure relates further to a method to detect compound-compound-interaction using the cytoplasmic protein complex, and to cells comprising such cytoplasmic protein complex. |
申请公布号 |
EP2681319(A1) |
申请公布日期 |
2014.01.08 |
申请号 |
EP20120706065 |
申请日期 |
2012.02.29 |
申请人 |
VIB VZW;UNIVERSITEIT GENT |
发明人 |
TAVERNIER, JAN;LIEVENS, SAMUEL |
分类号 |
C12N15/62;C12N9/12;C12N15/10 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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