发明名称 |
Paliperidone implant formulation |
摘要 |
<p>An injectable intramuscular depot composition suitable for forming an in situ solid implant in a body, comprisinga drug which is paliperidone and/or its pharmaceutical acceptable salts in any combination thereof, a biocompatible copolymer based on lactic and glycolic acid having a monomer ratio of lactic to glycolic acid in the range from 50:50 and a DMSO solvent, wherein the composition releases the drug with an immediate onset of action and continuously for at least 8 weeks and wherein the composition has a pharmacokinetic profile in vivo suitable for the formulation to be administered each 8 weeks or even longer periods.</p> |
申请公布号 |
EP2529757(B1) |
申请公布日期 |
2014.01.08 |
申请号 |
EP20120170366 |
申请日期 |
2012.05.31 |
申请人 |
LABORATORIOS FARMACEUTICOS ROVI, S.A. |
发明人 |
GUTIERRO ADURIZ, IBON;FRANCO RODRIGUEZ, GUILLERMO |
分类号 |
A61K47/34;A61K9/00;A61K31/519 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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