摘要 |
The present invention relates to a lipid nanoparticle system comprising a lipid component, a cationic surfactant, a non-ionic surfactant, a polysaccharide and, optionally, a positively charged peptide, useful for the release of pharmacologically active molecules, and especially for transfecting genetic material into cells and/or tissues. It also relates to methods for obtaining nanoparticles, to pharmaceutical compositions comprising it, as well as to the use thereof in gene therapy. |
申请人 |
UNIVERSIDAD DEL PAIS VASCO |
发明人 |
RODRIGUEZ GASCON, ALICIA;SOLINIS ASPIAZU, MARIA ANGELES;DEL POZO RODRIGUEZ, ANA;DELGADO SAN VICENTE, DIEGO;PEDRAZ MUNOZ, JOSE LUIS |