Compounds for the inhibition of mammalian Ste20-like kinase 1 (MST1) are disclosed, along with compositions comprising them and methods of their use in the treatment, management or prevention of an inflammatory or autoimmune diseases or disorders. Particular compounds are of the formula:
申请公布号
EP2681206(A1)
申请公布日期
2014.01.08
申请号
EP20120709439
申请日期
2012.03.02
申请人
LEXICON PHARMACEUTICALS, INC.
发明人
AUGERI, DAVID JOHN;BAGDANOFF, JEFFREY THOMAS;BAUGH, SIMON DAVID PETER;CARLSEN, MARIANNE;CARSON, KENNETH GORDON;GILLERAN, JOHN ANTHONY;HE, WEI;ORAVECZ, TAMAS;SALOJIN, KONSTANTIN;SUNG, LEONARD
