发明名称 Process for obtaining 3,3-diphenylpropylamines
摘要 The invention relates to a process for obtaining 3,3-diphenylpropylamines of general formula (I), particularly Fesoterodine, as well as their enantiomers, solvates and salts, comprising a chemoselective reduction of the acid group against the ester group in compounds of general formula (V), wherein R 1 is C 1 -C 8 alkyl; and R 3 and R 4 , independently of one another, represent H or C 1 -C 8 alkyl, or together form a ring of 3 to 7 members with the nitrogen to which they are bound. The invention also relates to the compounds of formula (V), as well as their enantiomers, solvates and salts.
申请公布号 EP2281801(B1) 申请公布日期 2014.01.08
申请号 EP20090382123 申请日期 2009.07.27
申请人 CRYSTAL PHARMA, S.A.U. 发明人 LORENTE BONDE-LARSEN, ANTONIO;MARTIN PASCUAL, PABLO;LADERAS MUNOZ, MARIO;GUTIERREZ FUENTES, LUIS GERARDO
分类号 C07C229/38;C07C213/08;C07C219/28 主分类号 C07C229/38
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