| 发明名称 |
GLA-DOMAINLESS FACTOR XA FOR TREATING HAEMOPHILIA A OR B WITH OR WITHOUT ANTIBODY |
| 摘要 |
The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor. |
| 申请公布号 |
EP2680876(A1) |
申请公布日期 |
2014.01.08 |
| 申请号 |
EP20120712302 |
申请日期 |
2012.02.29 |
| 申请人 |
UNIVERSITE JOSEPH FOURIER (GRENOBLE 1);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
POLACK, BENOIT;THOMAS, ALINE |
| 分类号 |
A61K38/48;A61P7/04;C07K14/745 |
主分类号 |
A61K38/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
