发明名称 |
ENHANCED TUMOR THERAPY BY TUMOR STEM CELL TARGETED ONCOLYTIC VIRUSES |
摘要 |
The invention relates to recombinant oncolytic viruses that target tumor stem cells and various uses of these recombinant viruses. In particular, an oncolytic virus comprising a recombinant binding domain specific for a tumor stem cell marker is disclosed. Furthermore, the use of such oncolytic viruses for the treatment of cancer is disclosed. |
申请公布号 |
EP2680867(A2) |
申请公布日期 |
2014.01.08 |
申请号 |
EP20120706618 |
申请日期 |
2012.03.05 |
申请人 |
BUNDESREPUBLIK DEUTSCHLAND, LETZTVERTRETEN DURCH DEN PRAESIDENTEN DES PAUL-EHRLICH-INSTITUTS PROF. DR. KLAUS CICHUTEK |
发明人 |
BUCHHOLZ, CHRISTIAN;BACH, PATRICIA;ABEL, TOBIAS |
分类号 |
A61K35/76;C07K14/705;C12N7/04 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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