| 发明名称 |
HIGH AFFINITY BINDING SITE OF HGFR AND METHODS FOR IDENTIFICATION OF ANTAGONISTS THEREOF |
| 摘要 |
<p>Use of a polynucleotide encoding or a polypeptide comprising at least the extra-cellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of pharmacologically active agents useful in the treatment of cancer, preferably a cancer with dysregulation of hepatocyte growth factor receptor.</p> |
| 申请公布号 |
CA2665958(C) |
申请公布日期 |
2014.01.07 |
| 申请号 |
CA20092665958 |
申请日期 |
2009.05.12 |
| 申请人 |
METHERESIS TRANSLATIONAL RESEARCH SA |
发明人 |
COMOGLIO, PAOLO MARIA;CARMINATI, PAOLO;MICHIELI, PAOLO;BASILICO, CRISTINA |
| 分类号 |
C12Q1/68;A61K38/18;A61K48/00;C07K14/71;C12N15/18;C12Q1/02;G01N33/28;G01N33/53;G01N33/566 |
主分类号 |
C12Q1/68 |
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