发明名称 Imaging agents for use in magnetic resonance blood flow/perfusion imaging
摘要 In one aspect, a method of imaging blood flow in a region of interest of a subject using magnetic resonance imaging (MRI) is provided. The method includes introducing an imaging agent into the subject, the imaging agent including a compound having at least one hyperpolarized nucleus having a T.sub.1 greater than 15 seconds and a water-octanol partition coefficient between -1 and 1, providing at least one excitation signal to the region of interest, the at least one excitation signal configured to invoke a nuclear magnetic resonance (NMR) effect at least in the introduced imaging agent, and detecting an NMR signal emitted by the region of interest in response to the at least one excitation signal. In another aspect, the imaging agent includes a carbon-13 enriched alcohol.
申请公布号 US8623327(B2) 申请公布日期 2014.01.07
申请号 US20070308439 申请日期 2007.06.19
申请人 ALSOP DAVID;VINOGRADOV ELENA;GRANT AARON K.;LENKINSKI ROBERT E.;BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 发明人 ALSOP DAVID;VINOGRADOV ELENA;GRANT AARON K.;LENKINSKI ROBERT E.
分类号 A61B5/055 主分类号 A61B5/055
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