| 发明名称 |
Purification of HBV antigens for use in vaccines |
| 摘要 |
The present invention relates to a method for the production of a hepatitis B antigen suitable for use in a vaccine, the method comprising purification of the antigen in the presence of cysteine, to vaccines comprising such antigens. |
| 申请公布号 |
US8624004(B2) |
申请公布日期 |
2014.01.07 |
| 申请号 |
US20080342220 |
申请日期 |
2008.12.23 |
| 申请人 |
DE-HEYDER KOEN;SCHU PETER;SERANTONI MICHELLE;VAN-OPSTAL OMER;GLAXOSMITHKLINE BIOLOGICALS, S.A. |
发明人 |
DE-HEYDER KOEN;SCHU PETER;SERANTONI MICHELLE;VAN-OPSTAL OMER |
| 分类号 |
A61K39/29;C12P21/02;A61K38/00;A61K39/00;A61K39/295;A61K39/39;C07K1/14;C07K14/02;C12N15/00 |
主分类号 |
A61K39/29 |
| 代理机构 |
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代理人 |
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| 主权项 |
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