发明名称 |
Rationelt konstruerede meganucleaser med ændret sekvensspecificitet og DNA-bindingsaffinitet |
摘要 |
<p>Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number of loci within the genome, as well as methods of gene therapy, for treatment of pathogenic infections, and for in vitro applications in diagnostics and research.</p> |
申请公布号 |
DK2484758(T3) |
申请公布日期 |
2014.01.06 |
申请号 |
DK20120162075T |
申请日期 |
2006.10.18 |
申请人 |
PRECISION BIOSCIENCES |
发明人 |
HELLINGA, HOMME, W.;SMITH, JAMES JEFFERSON;JANTZ, DEREK |
分类号 |
C12N9/22;C12N15/90 |
主分类号 |
C12N9/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|