KLUYVEROMYCES MARXIANUS STRAIN HAVING BLOCKED ETHANOL PRODUCTION PATHWAY, AND USE THEREOF

摘要

The present invention relates to a Kluyveromyces marxianus strain which is a Crabtree-negative yeast in which the pyruvate decarboxylase is inactivated in order to prevent ethanol fermentation, and to a yeast strain for producing various organic acids by introducing various exogenous genes to the Kluyveromyces marxianus strain. Further, the present invention relates to a method for producing lactic acids by culturing the strain. The mutant strain in which the pyruvate decarboxylase is inactivated according to the present invention does not produce ethanol during the production of lactic acids. The method of the present invention effectively produces organic acids through the strain that produces organic acids by introducing various exogenous genes to the strain.