发明名称 |
MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE |
摘要 |
Provided herein are modified Fc proteins comprising non-natural amino acid residues at site-specific positions, conjugates of the modified Fc proteins for therapy or diagnosis, compositions comprising the modified Fc proteins and conjugates thereof, methods of their production and methods of their use. The modified Fc proteins and conjugates are useful for methods of treatment and prevention, methods of detection and methods of diagnosis. |
申请公布号 |
WO2014004639(A1) |
申请公布日期 |
2014.01.03 |
申请号 |
WO2013US47838 |
申请日期 |
2013.06.26 |
申请人 |
SUTRO BIOPHARMA, INC. |
发明人 |
THANOS, CHRISTOPHER D.;MCEVOY, LESLIE;YIN, GANG;PENTA, KALYANI;BALIGA, RAMESH;BAJAD, SUNIL;POLLITT, SONIA;MURRAY, CHRIS;STEINER, ALEX;GILL, AVINASH |
分类号 |
A61K47/48;C07K16/28 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|