发明名称 INHIBITORS OF INFLUENZA VIRUSES REPLICATION
摘要 Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.
申请公布号 US2014005192(A1) 申请公布日期 2014.01.02
申请号 US201313918048 申请日期 2013.06.14
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 CHARIFSON PAUL S.;CLARK MICHAEL P.;BANDARAGE UPUL K.;DAVIES IOANA;DUFFY JOHN P.;GAO HUAI;FENG JUN;LIANG JIANGLIN;KENNEDY JOSEPH M.;LEDEBOER MARK W.;LEDFORD BRIAN;MALTAIS FRANCOIS;PEROLA EMANUELE
分类号 C07D471/04;A61K31/506;A61K31/5377;A61K45/06 主分类号 C07D471/04
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