发明名称 |
PROCESSES AND INTERMEDIATES FOR CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS |
摘要 |
Processes are provided which create an aldehyde methylene, or hydrated or hemiacetal methylene attached to a heteroatom of a 6 membered ring without going through an olefinic group and without the necessity of using an osmium reagent. In particular, a compound of formula (I) can be produced from (II) and avoid the use of an allyl amine: (formulae I and II) where R, P1 P3, R3 and Rx are as described herein. |
申请公布号 |
US2014005405(A1) |
申请公布日期 |
2014.01.02 |
申请号 |
US201314018863 |
申请日期 |
2013.09.05 |
申请人 |
VIIV HEALTHCARE COMPANY;SHIONOGI & CO., LTD.;SIONOGI & CO., LTD. |
发明人 |
JOHNS BRIAN;DUAN MAOSHENG;HAKOGI TOSHIKAZU |
分类号 |
C07D213/82;C07D213/807 |
主分类号 |
C07D213/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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