发明名称 IMMUNOTHERAPY OF CANCER USING GENETICALLY ENGINEERED GD2-SPECIFIC T CELLS
摘要 The present invention concerns immunotherapy for cancers having cells that comprise the ganglioside GD2 antigen. In specific embodiment, T cells having a chimeric receptor that targets GD2 is employed. In particular cases, the chimeric receptor comprises antibody, cytoplasmic signaling domain from the T cell receptor, and/or costimulatory molecule(s).
申请公布号 US2014004132(A1) 申请公布日期 2014.01.02
申请号 US201113820931 申请日期 2011.09.08
申请人 BRENNER MALCOLM;DOTTI GIANPIETRO;AHMED NABIL;ROSSIG CLAUDIA;GOTTSCHALK STEPHEN M.G.;GRADA ZAKARIA 发明人 BRENNER MALCOLM;DOTTI GIANPIETRO;AHMED NABIL;ROSSIG CLAUDIA;GOTTSCHALK STEPHEN M.G.;GRADA ZAKARIA
分类号 C12N5/0783;C07K16/18 主分类号 C12N5/0783
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