| 发明名称 |
SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF |
| 摘要 |
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc. |
| 申请公布号 |
US2014005191(A1) |
申请公布日期 |
2014.01.02 |
| 申请号 |
US201113884061 |
申请日期 |
2011.11.09 |
| 申请人 |
COBURN CRAIG A.;LIU KUN;MCEACHER ERNEST J.;MU CHANGWEI;SELNICK HAROLD G.;VOCADLO DAVID J.;WANG YAODE;WEI ZHONGYONG;ZHOU YUANXI;MERCK SHARP & DOHME CORP.;ALECTOS THERAPEUTICS INC. |
发明人 |
COBURN CRAIG A.;LIU KUN;MCEACHER ERNEST J.;MU CHANGWEI;SELNICK HAROLD G.;VOCADLO DAVID J.;WANG YAODE;WEI ZHONGYONG;ZHOU YUANXI |
| 分类号 |
C07D513/14 |
主分类号 |
C07D513/14 |
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