METHOD FOR PRODUCING 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE FROM 3-(METHYLTHIO)PROPANAL AND HYDROGEN CYANIDE
摘要
<p>A method for the production of 2-hydroxy-4-(methylthio)butyronitrile having good storage stability in a multi-zone reactor, is provided. 3-methylmercaptopropionaldehyde is reacted with hydrogen cyanide in the presence of a base as catalyst in a main reaction zone of the multizone reactor to form a reaction mixture comprising the 2-hydroxy-4-(methylthio)butyronitrile, unreacted 3-methylmercaptopropionaldehyde, the catalyst and residual amounts of gaseous hydrogen cyanide. The residual gaseous hydrogen cyanide is removed from the main reaction zone to an absorption and post-reaction zone of the reactor which comprises a mixture of 3-methylmercaptopropionaldehyde and the catalyst; and the gaseous hydrogen cyanide is further reacted with the 3-methylmercaptopropionaldehyde in the absorption and post reaction zone. A molar ratio of hydrogen cyanide to 3-(methylthio)propanal in the main reaction zone is from 0.98 to 1.03.</p>
申请公布号
EP2678312(A1)
申请公布日期
2014.01.01
申请号
EP20120704512
申请日期
2012.02.13
申请人
EVONIK DEGUSSA GMBH
发明人
BUSS, DIETER;STEURENTHALER, MARTIN;RINNER, MICHAEL, R.;KRETZ, STEPHAN;HASSELBACH, HANS JOACHIM;FINKELDEI, CASPAR-HEINRICH;KOERFER, MARTIN;ZACCHI, PABLO