发明名称 |
MYH10 AS A NEW DIAGNOSTIC MARKER OF PATHOLOGIES RESULTING FROM RUNX1 INACTIVATION |
摘要 |
The present invention relates to a method of diagnosing a pathology resulting from a runt-related transcription factor 1 (RUNX1) inactivation in a subject, which comprises the step of i) determining the platelets' myosin non-muscle heavy chain 10 (MYH10) expression level in a biological sample from said subject, and wherein a detectable platelets' MYH10 expression level is indicative of a pathology resulting from a runt-related transcription factor 1 (RUNX1) inactivation, and to a kit for diagnosing a pathology resulting from a runt-related transcription factor (RUNX1) inactivation in a subject comprising i) at least one antibody for determining the platelet MYH10 expression level in a biological sample from said subject, which can be used in a such a method. |
申请公布号 |
EP2678684(A1) |
申请公布日期 |
2014.01.01 |
申请号 |
EP20120705797 |
申请日期 |
2012.02.23 |
申请人 |
INSTITUT GUSTAVE ROUSSY (IGR) |
发明人 |
BLUTEAU, DOMINIQUE;CHANG-MARCHAND, YUNCHUA;FAVIER, RÉMI;LORDIER, LARISSA;RASLOVA, HANA;VAINCHENKER, WILLIAM |
分类号 |
G01N33/574;G01N33/68 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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