PRODUCTION OF HIGH LEVELS OF DHA IN MICROALGAE USING MODIFIED AMOUNTS OF CHLORIDE AND POTASSIUM
摘要
Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsaturated fatty acids by marine microorganisms while growing in low chloride media by manipulating sodium ion and potassium ion levels. The invention also relates to methods of production of highly unsaturated fatty acids by marine organisms at low pH levels, and includes methods for generation of low pH tolerant strains.
申请公布号
EP1702073(B1)
申请公布日期
2014.01.01
申请号
EP20040785345
申请日期
2004.10.01
申请人
DSM IP ASSETS B.V.
发明人
BEHRENS, PAUL, W.;THOMPSON, JOHN, M.;APT, KIRK;PFEIFER, JOSEPH, W., III;WYNN, JAMES, P.;LIPPMEIER, JAMES, CASEY;FICHTALI, JAOUAD;HANSEN, JON