发明名称 |
ANTIGEN SPECIFIC TREGS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS |
摘要 |
Antigen specific regulatory T cells are described and related compositions, methods and systems. Methods to generate an antigen specific anti-inflammatory regulatory T cell is provided, the method comprising contacting either a T cell or an antigen presenting cell with a zwitterionic polysaccharide conjugated to the antigen for a time and under condition to generate an antigen specific regulatory T cell that is capable of inhibiting a pro-inflammatory response against the antigen. |
申请公布号 |
EP2571982(A4) |
申请公布日期 |
2014.01.01 |
申请号 |
EP20110784368 |
申请日期 |
2011.05.20 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
ROUND, JUNE, L.;MAZMANIAN, SARKIS, K. |
分类号 |
C12N5/0783;A61K35/12;A61K39/00 |
主分类号 |
C12N5/0783 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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