发明名称 |
Immuno-based botulinum toxin serotype A activity assays |
摘要 |
The present specification discloses SNAP-25 compositions, methods of making alpha-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, alpha-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing alpha-BoNT/A antibodies. |
申请公布号 |
US8618261(B2) |
申请公布日期 |
2013.12.31 |
申请号 |
US20100723474 |
申请日期 |
2010.03.12 |
申请人 |
ESTER FERNANDEZ-SALAS;WANG JOANNE;GARAY PATTON;WONG LINA S.;HODGES D. DIANNE;AOKI KEI ROGER;ALLERGAN, INC. |
发明人 |
ESTER FERNANDEZ-SALAS;WANG JOANNE;GARAY PATTON;WONG LINA S.;HODGES D. DIANNE;AOKI KEI ROGER |
分类号 |
C07K16/00 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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