| 发明名称 |
4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY |
| 摘要 |
<p>The invention relates to the 5S,4R-enantiomer of 2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide with cognition enhancing activity of high pharmacological value and to its preparation method which includes the synthesis of 5S-methyl-4R-phenylpyrrolidin-2-one, its N-alkylation with ethyl haloacetate and the treatment of intermediate ethyl 2-(5S-methyl-2-oxo-4R-phenyl-pyrrolidin-1-yl)-acetate with ammonia.</p> |
| 申请公布号 |
SI2496555(T1) |
申请公布日期 |
2013.12.31 |
| 申请号 |
SI20100030416T |
申请日期 |
2010.11.04 |
| 申请人 |
GRINDEKS, A JOINT STOCK COMPANY |
发明人 |
KALVINS IVARS;LEBEDEVS ANTONS;CERNOBROVIJS ALEKSANDRS;DAMBROVA MAIJA;ZVEJNIECE LIGA;VORONA MAKSIMS;VEINBERGS GRIGORIJS |
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