FIBROBLAST-MOBILIZATION AGENT CONTAINING A G-CSF FOR REPAIR OF MYOCARDIAL INFARCT LESION

摘要

The object of the present invention is to achieve simple recruitment of fibroblasts into wounded tissues and engraftment of the fibroblasts in the wounded tissues, thereby healing the wounds without requiring fibroblast transplantation. Upon G-CSF administration, fibroblasts migrate into myocardial infarct lesions and prevent a reduction in cardiac function, thus alleviating cardiac remodeling.