发明名称 |
CYLODEXTRIN COMPLEXATION METHODS FOR FORMULATING PEPTIDE PROTEASOME INHIBITORS |
摘要 |
<p>This disclosure provides methods for formulating compositions comprising one ormore peptide proteasome inhibitors and a cyclodextrin, particularly a substitutedcyclodextrin. Such methods substantially increase the solubility and stability of these proteasome inhibitors and facilitate both their manufacture and administration.</p> |
申请公布号 |
SG194417(A1) |
申请公布日期 |
2013.12.30 |
申请号 |
SG20120084075 |
申请日期 |
2012.09.13 |
申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
LEWIS, EVAN;SHWONEK, PETER;DALZIEL, SEAN;JUMAA, MOUHANNAD |
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