发明名称 |
METHOD FOR REMOVING UNMODIFIED HEMOGLOBIN FROM CROSS-LINKED HEMOGLOBINSOLUTIONS INCLUDING POLYMERIC HEMOGLOBIN WITH HIGH TEMPERATURES SHORT TIME HEATTREATMENT APPARATUS |
摘要 |
<p>A method heat treatment of cross-linked hemoglobin solutions including polymeric hemoglobin is disclosed. The method involves contacting the hemoglobin solution with a high temperature short time heat treatment apparatus. The high temperature short time process thermally denatures unmodified tetrameric hemoglobin (hemoglobin dimer form), protein impurities (e.g. immunoglobin-G, serum albumin), bacteria, and viruses so that renal injury, vascular detrimental effects and other toxicity reactions can be avoided.</p> |
申请公布号 |
SG194677(A1) |
申请公布日期 |
2013.12.30 |
申请号 |
SG20130080080 |
申请日期 |
2012.04.23 |
申请人 |
WONG, BING LOU;KWOK, SUI YI |
发明人 |
WONG, BING LOU;KWOK, SUI YI |
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