METHOD FOR IMPROVING PROTEIN RAPIDLY

摘要

The purpose of the present invention is to provide a method for producing or improving a protein, particularly an antibody. The present invention is a gene construct in which at least an arbitrary gene and a drug-resistant gene are arranged between two site-specific recombinant enzyme target sequences, wherein one of the site-specific recombinant enzyme target sequences, the arbitrary gene, the drug-resistant gene and the other of the site-specific recombinant enzyme target sequences are arranged in this order as observed from the upstream side of the gene construct and only the drug-resistant gene is arranged in a reversed direction.