The disclosure relates to di-aliphatic substituted PEGylated lipids and to methods of their preparation. The disclosure also relates to lipid conjugates containing di-aliphatic substituted PEGylated lipids, and to the use of di-aliphatic substituted PEGylated-lipid conjugates in drug delivery.
申请公布号
WO2013049328(A9)
申请公布日期
2013.12.27
申请号
WO2012US57527
申请日期
2012.09.27
申请人
ALNYLAM PHARMACEUTICALS, INC.;TAKEDA PHARMACEUTICAL COMPANY LIMITED