Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) broadly neutralizing antibodies having improved potency and breadth for neutralizing a range of HIV strains. Combinations of broadly neutralizing antibodies can also improve potency over a single antibody composition.
申请公布号
WO2013192589(A1)
申请公布日期
2013.12.27
申请号
WO2013US47183
申请日期
2013.06.21
申请人
CALIFORNIA INSTITUTE OF TECHNOLOGY
发明人
DISKIN, RON;WEST, ANTHONY, P.;NUSSENZWEIG, MICHEL, C.;BJORKMAN, PAMELA, J.