ANALYTICAL METHOD ON THE BASIS OF ELECTRON SPIN RESONANCE (ESR) AND PROBE|MOLECULE

摘要

The present application relates to an electron spin resonance (ESR) analytical method comprising: providing a probe molecule capable of binding selectively to a target, wherein a paramagnetic moiety is bound to the probe molecule via two thioether linkages, and an electron spin resonance signal of the probe molecule bound to the target is different from an electron spin resonance signal of the probe molecule that is not bound to the target, contacting the probe molecule with a first sample, which may or may not comprise the target, to form a mixed sample and obtaining an electron spin resonance signal of the mixed sample. Probe molecules, molecules for producing the probe molecules, and an apparatus is also described.