发明名称 |
Methods For Identifying Compounds That Modulate Untranslated Region-Dependent Gene Expression And Methods Of Using Same |
摘要 |
The present invention relates to methods for identifying compounds that modulate untranslated region-dependent expression of a target gene. The invention particularly relates to using untranslated regions of a target gene or fragments thereof linked to a reporter gene to identify compounds that modulate untranslated region-dependent expression of a target gene. The methods of the present invention provide a simple, sensitive assay for high-throughput screening of libraries of compounds to identify pharmaceutical leads. |
申请公布号 |
US2013347133(A1) |
申请公布日期 |
2013.12.26 |
申请号 |
US201313873543 |
申请日期 |
2013.04.30 |
申请人 |
PTC THERAPEUTICS, INC.;PTC THERAPEUTICS, INC. |
发明人 |
CAO LIANGXIAN;TRIFILLIS PANAYIOTA |
分类号 |
C12Q1/68;C07K14/52;C12N15/10 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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