摘要 |
PROBLEM TO BE SOLVED: To provide co-administering an antiplatelet agent and an acid inhibitor, and oral dosage forms containing a combination of an antiplatelet agent and an acid inhibitor, for preventing or ameliorating the gastrointestinal disorders associated with antiplatelet agents.SOLUTION: Oral dosage comprises an adenosine diphosphate antagonist in combination with an acid inhibitor, and may comprise a variety of acid inhibitors including, but not limited to, proton pump inhibitors, H2 blockers, and alkalizing agents. In some embodiments, the oral dosage form and/or active form is at least partially enteric-coated. |