发明名称 Pleuromutilin derivatives
摘要 <p>A compound of formula (I) wherein Y is oxygen or sulfur, and X 1 , X 2 and X 3 are independently hydrogen, halogen, hydroxy or linear or branched (C 1-6 )alkyl, or hydroxy-(C 1-6 )alkyl or (C 1-6 )alkoxy-(C 1-6 )alkyl, mono- or dihalogenated (C 1-6 )alkyl, amino-(C 1-6 )alkyl, hydroxy-(C 1-6 )alkyl, with the provisos that (1) at least one of X 1 , X 2 and X 3 is not hydrogen, and (2) X 2 is not hydroxy when X 1 and X 3 are hydrogen are useful in the treatment of diseases mediated by microbes.</p>
申请公布号 EP2176211(B1) 申请公布日期 2013.12.25
申请号 EP20080772584 申请日期 2008.07.11
申请人 NABRIVA THERAPEUTICS AG 发明人 THIRRING, KLAUS;HEILMAYER,WERNER
分类号 C07C69/712;A61K31/215;A61P31/04;C07C323/52 主分类号 C07C69/712
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