The present invention relates to assays for monitoring activity of OGFOD1 activity, in particular, to assays for identifying modulators of OGFOD1 activity. The invention also relates to assays to monitor the prolyl hydroxylase activity of OGFOD1 on its substrate, the human ribosomal protein RPS23. The invention also enables the introduction of 3-hydroxyprolyl residues into peptides and proteins.
申请公布号
EP2675912(A1)
申请公布日期
2013.12.25
申请号
EP20120703873
申请日期
2012.02.10
申请人
ISIS INNOVATION LTD
发明人
SCHOFIELD, CHRISTOPHER JOSEPH;WOLF, ALEXANDER;GE, WEI;THALHAMMER, ARMIN;LOENARZ, CHRISTOPH;RATCLIFFE, PETER JOHN;COCKMAN, MATTHEW EDWARD
