发明名称 |
Preparation method for caspofungin analog |
摘要 |
Disclosed is a preparation method for a caspofungin analog, comprising the steps: (a) a compound as represented in Formula 2 and a strong leaving group 5 are mixed to obtain a compound as represented in Formula 3; (b) the compound as represented in Formula 3 and ethylenediamine are mixed to obtain a compound as represented in Formula 4; and, (c) the compound as represented in Formula 4 is mixed with a hydroxyl protection agent, and then a borane complex is mixed in to obtain a compound as represented in Formula 1. |
申请公布号 |
GB2503348(A) |
申请公布日期 |
2013.12.25 |
申请号 |
GB20130009925 |
申请日期 |
2011.11.10 |
申请人 |
SHANGHAI TECHWELL BIOPHARMACEUTICAL CO. LTD |
发明人 |
MING LI;ZHIJUN TANG;XIAOMING JI;BINGMING HE |
分类号 |
C07K1/06;A61K38/12;C07K7/56 |
主分类号 |
C07K1/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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