| 摘要 |
The present invention provides a composition for diagnosing amyloid-related diseases, comprising a compound represented by general formula (I):
wherein X represents O or the like; R 1 , R 3 , R 4 , R 5 , R 6 , R 8 and R 9 represent a hydrogen atom or the like; R 2 represents a halogen atom or the like; and R 7 represents a dimethylamino group or the like;
or the compound labeled with a radionuclide, or a pharmaceutically acceptable salt of the compound or the labeled compound. The compound represented by general formula (I) has all of the following properties: high binding specificity to amyloid ² protein, high permeability through the blood-brain barrier, and rapid clearance from sites without senile plaques in the brain. |
