发明名称 |
COMPOSITION FOR INHIBITING AGING COMPRISING MDM2 INHIBITOR |
摘要 |
The present invention relates to a composition for antiaging which includes a MDM2 inhibitor as an active ingredient and, more specifically, to a composition for preventing or treating aging or aging related diseases which includes a mouse double minute 2 (MDM2) inhibitor as an active ingredient. The MDM2 inhibitor according to the present invention has excellent effects of producing inflammatory cytokine and suppressing cytotoxic Th17 cells which secret the same and enhances activation of immune regulatory T cells (Treg) which suppresses immunocytes which are abnormally activated and controls inflammation reaction. In addition, the MDM2 inhibitor has activities of incresing expression of SOCS3 which can suppress activities of STAT3 and can be effectively used for manufacturing medicines which can suppress aging with various immune responses by having excellent antiaging effects specially when elders are treated with the MDM2 inhibitor. |
申请公布号 |
KR20130139512(A) |
申请公布日期 |
2013.12.23 |
申请号 |
KR20120063017 |
申请日期 |
2012.06.13 |
申请人 |
CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATIONFOUNDATION |
发明人 |
KIM, HO YOUN;CHO, MI LA;JHUN, JOO YEON;BYUN, JAE KYEONG |
分类号 |
A61K48/00;A61K31/7088;A61K31/7105;A61P17/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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