| 摘要 |
FIELD: chemistry.SUBSTANCE: method involves sterilising filtration of a bulk manufactured biopolymer by passing through a membrane which is suitable for sterilising filtration; and concentrating the sterile biopolymer by ultrafiltration to concentration of 0.8-3.0% wt/vol. Concentration of the soluble, bulk manufactured biopolymer at the sterilising filtration step is less than 0.2%. In one of the versions, the biopolymer is soluble. In one of the versions, hyaluronic acid is used as the biopolymer.EFFECT: invention enables to obtain a highly pure viscoelastic biopolymer which is suitable for medical use without disrupting the biopolymer structure during sterilising filtration.19 cl |
