| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to substituted 4-aminocyclohexane derivatives of general formula I:where: Rand Rindependently denote C-alkyl, H or Rand Rtogether with an N tom form a (CH), (CH)ring; Roptionally denotes a phenyl or thienyl linked through a C-alkyl chain, each unsubstituted; or an unsubstituted C-alkyl; Rdenotes indole, pyrrolo[2,3-b]pyridine, pyrrolo[2,3-c]pyridine, pyrrolo[3,2-c]pyridine, pyrrolo[3,2-b]pyridine, optionally mono- or multi-substituted with a substitute selected from a group comprising F, CI, Br, CN, CH, CH,' NH, tert-butyl, Si(ethyl), Si(methyl)(tert-butyl), SOCH, SO-phenyl, C(O)CH, NO, SH, CF, OCF, OH, OCH, OCH, N(CH); in form of a racemate; enantiomers, diastereomers, mixtures of enantiomers or diastereomers or separately an enantiomer or diastereomers; bases and/or salts of physiologically compatible acids or cations; as well as a drug based on compounds I for treating neuropathic pain.EFFECT: improved properties.14 cl, 73 ex |
