发明名称 Cleavable lipids
摘要 Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent iransfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids.
申请公布号 AU2012267578(A1) 申请公布日期 2013.12.19
申请号 AU20120267578 申请日期 2012.06.08
申请人 SHIRE HUMAN GENETIC THERAPIES, INC. 发明人 HEARTLEIN, MICHAEL;GUILD, BRAYDON CHARLES;DEROSA, FRANK;ZHANG, JERRY CHI
分类号 C07D233/64;A61K9/127;A61K31/4164;C07C323/00 主分类号 C07D233/64
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