发明名称 Membrane Encapsulated Nanoparticles and Method of Use
摘要 Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided.
申请公布号 US2013337066(A1) 申请公布日期 2013.12.19
申请号 US201313827906 申请日期 2013.03.14
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 ZHANG LIANGFANG;HU CHE-MING (JACK);FANG RONNIE HONGBO;COPP JONATHAN
分类号 A61K9/14;A61K45/06 主分类号 A61K9/14
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