发明名称 |
Formulations of recombinant furin |
摘要 |
The present application provides stabilized formulations of furin (e.g., rfurin) containing a sugar, sugar alcohol, and/or non-ionic surfactant. As compared to non-stabilized compositions, the furin formulations disclosed herein retain greater amounts of furin activity and monomeric furin content, while reducing furin aggregation when stored and/or subjected to mechanical stress. Also provided are methods for stably diluting furin (e.g., rfurin) compositions. |
申请公布号 |
AU2012261813(A1) |
申请公布日期 |
2013.12.19 |
申请号 |
AU20120261813 |
申请日期 |
2012.06.04 |
申请人 |
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A. |
发明人 |
HASSLACHER, MEINHARD;CITKOWICZ, ANDRZEJ;WHITE, CATHERINE;FRANKE, KEN |
分类号 |
A61K47/02;A61K47/10;A61K47/12;A61K47/26;C12N9/64 |
主分类号 |
A61K47/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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