发明名称 |
METHODS AND MODELS FOR ASSESSING ANTI-AGING BENEFITS OF AGENTS |
摘要 |
A screening method for identifying an agent as effective for providing an anti-aging skin benefit is provided. The screening method includes culturing first and second human skin samples from about 3 days to about 19 days, wherein the first and second human skin samples are derived from a human skin surgical waste tissue. The first human skin sample is contacted with at least one test agent. The second human skin sample is contacted with a positive control. Transcriptional profiles are generated from the first and second human skin samples, and the at least one test agent is identified as effective for providing an anti-aging skin benefit when the transcriptional profiles of at least two genes show a similar directional change in comparison to one or more untreated control tissue samples. |
申请公布号 |
US2013337087(A1) |
申请公布日期 |
2013.12.19 |
申请号 |
US201313919325 |
申请日期 |
2013.06.17 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
FINLAY DEBORAH RUTH;OSBORNE ROSEMARIE;BASCOM CHARLES CARSON |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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