ENHANCING THE STABILITY AND PURITY AND INCREASING THE BIOAVAILABILITY OF HUMAN MILK OLIGOSACCHARIDES OR PRECURSORS OR BLENDS THEREOF

摘要

The present application discloses a method for enhancing the stability of a human milk oligosaccharide (HMO) or a HMO precursor or a HMO blend when stored for extended periods at temperatures above 25 °C by spray-drying an aqueous solution of the HMO or HMO precursor to remove at least 90 % of the water and providing a HMO or a HMO precursor or a HMO blend with a specific glass transition temperature. Also disclosed is a method for removing organic solvent residues from a human milk oligosaccharide (HMO) or a HMO precursor or a HMO blend by spray drying. Also disclosed is a method of enhancing the bioavailability of a human milk oligosaccharide (HMO) or a HMO precursor or a HMO blend by spray drying.