| 摘要 |
PROBLEM TO BE SOLVED: To provide a process for manufacturing multiparticulate pharmaceutical compositions.SOLUTION: A process for manufacturing multiparticulate pharmaceutical compositions using a roller compactor is provided. The process is particularly useful for producing minitablets without the need of the use of a tablet press. The roller compactor features rolls having depressions or molds on a surface. Upon compaction of pharmaceutical blend, the minitablets are formed by the depressions on the roller surfaces. |
