发明名称 |
Immunogenic composition for treatment of hepatitis C, a method for preparing the composition and use thereof for treating hepatitis C |
摘要 |
This disclosure provides an immunogenic composition comprising an amount of isolated dendritic cells comprising at least one fragment of a hepatitis C protein selected from the group consisting of the core protein of hepatitis C and the NS3 protein of hepatitis C, the fragment does not suppress activity of dendritic cells and is effective to produce an immunogenic response against hepatitis C infection and optionally T-lymphocytes activated for a Th1 response. This disclosure also provides a method and a kit for preparing the above composition. Further, this disclosure provides a method for treating or reducing the severity of hepatitis C and a method for enhancing immunoresponse in a patient suffering from hepatitis C virus infection by administering to the patient in need of the treatment the above composition. Finally, this disclose provides a use of the above composition for treating hepatitis C virus infection. |
申请公布号 |
US2013337001(A1) |
申请公布日期 |
2013.12.19 |
申请号 |
US201213686425 |
申请日期 |
2012.11.27 |
申请人 |
FILATOV MIKHAIL VALENTINOVICH |
发明人 |
FILATOV MIKHAIL VALENTINOVICH |
分类号 |
A61K39/29;A61K35/14 |
主分类号 |
A61K39/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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