发明名称 |
Method of preparing composite granule comprising low-substituted hydroxypropyl cellulose and rapid release preparation |
摘要 |
Provided is a base material for dry direct tableting, the material being excellent in a binding property and disintegrability. More specifically, provided is a method of preparing a composite granule comprising at least a step of granulating a second sugar or sugar alcohol while adding thereto an aqueous dispersion comprising at least low-substituted hydroxypropyl cellulose having a degree of hydroxypropoxy substitution of 5 to 16% by weight, polyvinyl alcohol, a first sugar or sugar alcohol, and water. |
申请公布号 |
EP2674149(A1) |
申请公布日期 |
2013.12.18 |
申请号 |
EP20130169048 |
申请日期 |
2013.05.23 |
申请人 |
SHIN-ETSU CHEMICAL CO., LTD. |
发明人 |
MARUYAMA, NAOSUKE;HIRAMA, YASUYUKI |
分类号 |
A61K9/00;A61K9/16;A61K9/20;A61K31/167;A61K31/375;A61K47/38 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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