发明名称 |
GBS toxin receptor compositions and methods of use |
摘要 |
Methods are provided for preventing or attenuating pathoangiogenic conditions by administering at least one GBS toxin receptor polypeptide or at least one immunogenic fragment thereof. Also provided are a composition that includes a GBS toxin receptor polypeptide and a method for making such a composition. In another embodiment of the invention, immunized animals also receive GBS toxin, immunocompatible antibodies to the GBS toxin receptor, and/or expanded autologous T cells to the GBS toxin receptor. Also included in this invention are methods of identifying additional GBS toxin receptors. |
申请公布号 |
US8609614(B2) |
申请公布日期 |
2013.12.17 |
申请号 |
US201113022357 |
申请日期 |
2011.02.07 |
申请人 |
HELLERQVIST CARL G.;FU CHANGLIN;VANDERBILT UNIVERSITY |
发明人 |
HELLERQVIST CARL G.;FU CHANGLIN |
分类号 |
A61K38/17;A61K38/03;C07K14/435 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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