发明名称 |
RECOMBINANT POLYPEPTIDE PRODUCTION METHOD. |
摘要 |
<p>Provided is a method capable of producing a protein in a large amount using cultured animal cells, comprising culturing cells expressing APES (antibody production enhancing sequence) and transfected with a DNA encoding a desired polypeptide, thereby producing the desired polypeptide. APES contains a base sequence related to NfkBia and has a function of decreasing the intracellular expression of NfkBia.</p> |
申请公布号 |
MX2013011355(A) |
申请公布日期 |
2013.12.16 |
申请号 |
MX20130011355 |
申请日期 |
2012.03.30 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
TABUCHI, HISAHIRO;SUGIYAMA, TOMOYA |
分类号 |
C12P21/02;A61K38/00;A61K39/395;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/113;C12P21/08 |
主分类号 |
C12P21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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